› 108d

Solution NMR

THE SOLUTION STRUCTURE OF A DNA COMPLEX WITH THE FLUORESCENT BIS INTERCALATOR TOTO DETERMINED BY NMR SPECTROSCOPY

Released:
DOI: 10.2210/pdb108d/pdb
PDB entry 108d coloured by chain, ensemble of 40 models, front view.
PDB entry 108d coloured by chain, ensemble of 40 models, side view.
PDB entry 108d coloured by chain, ensemble of 40 models, top view.
Source organism: Synthetic construct
Primary publication:
Solution structure of a DNA complex with the fluorescent bis-intercalator TOTO determined by NMR spectroscopy.
Spielmann HP, Wemmer DE, Jacobsen JP
Biochemistry 34 8542-53 (1995)
PMID: 7612596

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113299 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*CP*GP*CP*TP*AP*GP*CP*G)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 8 nucleotides
Theoretical weight: 2.43 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand TOT 1 x TOT
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: MOLECULAR DYNAMICS, MATRIX RELAXATION
Expression system: Not provided

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Citations

2 review citations

DNA in nanochannels--directly visualizing genomic information.
Persson et al. (2010)
1 more

14 mentions without citation

Bi-allelic Variants in METTL5 Cause Autosomal-Recessive Intellectual Disability and Microcephaly.
Richard et al. (2019)
13 more