› 153d

X-ray diffraction
2.9Å resolution

CRYSTAL STRUCTURE OF A MISPAIRED DODECAMER, D(CGAGAATTC(O6ME)GCG)2, CONTAINING A CARCINOGENIC O6-METHYLGUANINE

Released:
DOI: 10.2210/pdb153d/pdb
PDB entry 153d coloured by chain, front view.
PDB entry 153d coloured by chain, side view.
PDB entry 153d coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Crystal structure of a mispaired dodecamer, d(CGAGAATTC(O6Me)GCG)2, containing a carcinogenic O6-methylguanine.
Ginell SL, Vojtechovsky J, Gaffney B, Jones R, Berman HM
Biochemistry 33 3487-93 (1994)
PMID: 8142345

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113342 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*CP*GP*AP*GP*AP*AP*TP*TP*CP*(6OG)P*CP*G)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 12 nucleotides
Theoretical weight: 3.7 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand 6OG 2 x 6OG

Experiments and Validation Details

Entry percentile scores
X-ray source: ENRAF-NONIUS FR571
Spacegroup: P212121
Unit cell:
a: 25.13Å b: 40.45Å c: 64.51Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.169 not available not available
Expression system: Not provided

Quick links

Citations

2 review citations

DNA structural forms.
Hartmann et al. (1996)
1 more

1 mention without citation

Molecular phyloecology suggests a trophic shift concurrent with the evolution of the first birds.
Wu Y. (2021)