› 1a4j

X-ray diffraction
2.1Å resolution

DIELS ALDER CATALYTIC ANTIBODY GERMLINE PRECURSOR

Released:
DOI: 10.2210/pdb1a4j/pdb
PDB entry 1a4j coloured by chain, front view.
PDB entry 1a4j coloured by chain, side view.
PDB entry 1a4j coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Immunological origins of binding and catalysis in a Diels-Alderase antibody.
Romesberg FE, Spiller B, Schultz PG, Stevens RC
Science 279 1929-33 (1998)
PMID: 9506942

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-224976 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Immunoglobulin kappa constant Chains: A, L
Molecule details ›
Chains: A, L
Length: 217 amino acids
Theoretical weight: 23.71 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P01834 (Residues: 1-105; Coverage: 98%)
Gene name: IGKC
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
IMMUNOGLOBULIN, DIELS ALDER CATALYTIC ANTIBODY (HEAVY CHAIN) Chains: B, H
Molecule details ›
Chains: B, H
Length: 219 amino acids
Theoretical weight: 23.59 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: C2
Unit cell:
a: 158.9Å b: 49.33Å c: 145Å
α: 90° β: 108.74° γ: 90°
R-values:
R R work R free
0.229 0.229 0.292
Expression system: Escherichia coli

Quick links

Citations

23 review citations

Showing your ID: intrinsic disorder as an ID for recognition, regulation and cell signaling.
Uversky et al. (2005)
22 more

10 mentions without citation

A Review of Deep Learning Methods for Antibodies.
Graves et al. (2020)
9 more