Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Immunoglobulin C1-set
- MHC class I alpha chain, alpha1 alpha2 domains
- Beta-2-Microglobulin
- Immunoglobulin/major histocompatibility complex, conserved site
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like domain
- Immunoglobulin-like fold
- MHC classes I/II-like antigen recognition protein
2 more domains
Structure domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158321 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hereditary hemochromatosis protein
Molecule details ›
Chains: A, C
Length: 275 amino acids
Theoretical weight: 32.34 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
Sequence domains:
Structure domains:
Length: 275 amino acids
Theoretical weight: 32.34 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
- Canonical:
Q30201 (Residues: 23-297; Coverage: 84%)
Sequence domains:
Structure domains:
Beta-2-microglobulin
Molecule details ›
Chains: B, D
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSLS BEAMLINE X4A
Spacegroup:
P212121
Expression system: Cricetulus griseus
