› 1a7s

X-ray diffraction
1.12Å resolution

ATOMIC RESOLUTION STRUCTURE OF HBP

Released:
DOI: 10.2210/pdb1a7s/pdb
PDB entry 1a7s coloured by chain, front view.
PDB entry 1a7s coloured by chain, side view.
PDB entry 1a7s coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Atomic resolution structure of human HBP/CAP37/azurocidin.
Karlsen S, Iversen LF, Larsen IK, Flodgaard HJ, Kastrup JS
Acta Crystallogr D Biol Crystallogr 54 598-609 (1998)
PMID: 9761855

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148866 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Azurocidin Chain: A
Molecule details ›
Chain: A
Length: 225 amino acids
Theoretical weight: 24.3 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P20160 (Residues: 27-251; Coverage: 97%)
Gene name: AZU1
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
3 bound ligands:
Ligand NAG 1 x NAG
Ligand CL 1 x CL
Ligand EOH 15 x EOH
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X31
Spacegroup: P212121
Unit cell:
a: 38.22Å b: 65.16Å c: 101.58Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.159 not available 0.189
Expression system: Spodoptera frugiperda

Quick links

Citations

1 review citation

The role of neutrophil granule proteins in neuroinflammation and Alzheimer's disease.
Stock et al. (2018)
7 other articles

15 mentions without citation

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Canutescu et al. (2003)
14 more