Function and Biology Details
Reaction catalysed:
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158135 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Rho GTPase-activating protein 1
Molecule details ›
Chains: A, B, C
Length: 199 amino acids
Theoretical weight: 22.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: RhoGAP domain
Structure domains: Rho GTPase activation protein
Length: 199 amino acids
Theoretical weight: 22.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q07960 (Residues: 233-431; Coverage: 45%)
Sequence domains: RhoGAP domain
Structure domains: Rho GTPase activation protein
Cell division control protein 42 homolog
Molecule details ›
Chains: D, E, F
Length: 177 amino acids
Theoretical weight: 19.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Length: 177 amino acids
Theoretical weight: 19.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P60953 (Residues: 2-177; Coverage: 92%)
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
