› 1awz

Solution NMR

3D SOLUTION STRUCTURE OF HUMAN ANGIOGENIN DETERMINED BY 1H, 15N NMR SPECTROSCOPY, 30 STRUCTURES

Released:
DOI: 10.2210/pdb1awz/pdb
PDB entry 1awz coloured by chain, ensemble of 30 models, front view.
PDB entry 1awz coloured by chain, ensemble of 30 models, side view.
PDB entry 1awz coloured by chain, ensemble of 30 models, top view.
Source organism: Homo sapiens
Primary publication:
Three-dimensional solution structure of human angiogenin determined by 1H,15N-NMR spectroscopy--characterization of histidine protonation states and pKa values.
Lequin O, Thüring H, Robin M, Lallemand JY
Eur J Biochem 250 712-26 (1997)
PMID: 9461294

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137273 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Angiogenin Chain: A
Molecule details ›
Chain: A
Length: 123 amino acids
Theoretical weight: 14.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli B
UniProt:
  • Canonical: P03950 (Residues: 25-147; Coverage: 100%)
Gene names: ANG, RNASE5
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY, SIMULATED ANNEALING
Expression system: Escherichia coli B

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Citations

2 review citations

Targeting intrinsically disordered proteins in neurodegenerative and protein dysfunction diseases: another illustration of the D(2) concept.
Uversky VN. (2010)
1 more

3 mentions without citation

Human antimicrobial peptides and proteins.
Wang G. (2014)
2 more