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Solution NMR

NMR STRUCTURE OF THE COMPLEX BETWEEN THE C32S-Y7V MUTANT OF THE NSH3 DOMAIN OF GRB2 WITH A PEPTIDE FROM SOS, 10 STRUCTURES

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-150827 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Growth factor receptor-bound protein 2 Chain: A
Molecule details ›
Chain: A
Length: 56 amino acids
Theoretical weight: 6.48 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P62993 (Residues: 1-56; Coverage: 26%)
Gene names: ASH, GRB2
Sequence domains: SH3 domain
Structure domains: SH3 Domains
Protein son of sevenless Chain: B
Molecule details ›
Chain: B
Length: 10 amino acids
Theoretical weight: 1.17 KDa
Source organism: Drosophila melanogaster
Expression system: Not provided
UniProt:
  • Canonical: P26675 (Residues: 1342-1351; Coverage: 1%)
Gene names: CG7793, Sos

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: SIMULATED ANNEALING ENERGY MINIMIZATION
Expression system: Not provided