› 1b3k

X-ray diffraction
2.99Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138523 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Plasminogen activator inhibitor 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 379 amino acids
Theoretical weight: 42.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05121 (Residues: 24-402; Coverage: 100%)
Gene names: PAI1, PLANH1, SERPINE1
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SIEMENS
Spacegroup: P1
Unit cell:
a: 65.472Å b: 74.93Å c: 103.691Å
α: 90.97° β: 93.33° γ: 115.94°
R-values:
R R work R free
0.247 0.247 0.292
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Serpins in thrombosis, hemostasis and fibrinolysis.
Rau et al. (2007)
8 more

14 mentions without citation

An overview of the serpin superfamily.
Law et al. (2006)
13 more