› 1bg2

X-ray diffraction
1.8Å resolution

HUMAN UBIQUITOUS KINESIN MOTOR DOMAIN

Released:
DOI: 10.2210/pdb1bg2/pdb
PDB entry 1bg2 coloured by chain, front view.
PDB entry 1bg2 coloured by chain, side view.
PDB entry 1bg2 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the kinesin motor domain reveals a structural similarity to myosin.
Kull FJ, Sablin EP, Lau R, Fletterick RJ, Vale RD
Nature 380 550-5 (1996)
PMID: 8606779

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152549 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kinesin-1 heavy chain Chain: A
Molecule details ›
Chain: A
Length: 325 amino acids
Theoretical weight: 36.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P33176 (Residues: 1-325; Coverage: 34%)
Gene names: KIF5B, KNS, KNS1
Sequence domains: Kinesin motor domain
Structure domains: Kinesin motor domain

Ligands and Environments

3 bound ligands:
Ligand MG 1 x MG
Ligand ACT 3 x ACT
Ligand ADP 1 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P212121
Unit cell:
a: 48.54Å b: 67.94Å c: 112.95Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.216 0.288
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

90 review citations

Intrinsically disordered protein.
Dunker et al. (2001)
89 more

45 mentions without citation

Structures of kinesin motor proteins.
Marx et al. (2009)
44 more