› 1boy

X-ray diffraction
2.2Å resolution

EXTRACELLULAR REGION OF HUMAN TISSUE FACTOR

Released:
DOI: 10.2210/pdb1boy/pdb
PDB entry 1boy coloured by chain, front view.
PDB entry 1boy coloured by chain, side view.
PDB entry 1boy coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the extracellular region of human tissue factor.
Harlos K, Martin DM, O'Brien DP, Jones EY, Stuart DI, Polikarpov I, Miller A, Tuddenham EG, Boys CW
Nature 370 662-6 (1994)
PMID: 8065454

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146733 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tissue factor Chain: A
Molecule details ›
Chain: A
Length: 219 amino acids
Theoretical weight: 24.83 KDa
Source organism: Homo sapiens
Expression system: PERIPLASMIC SECRETION (U.S PAT 4963,495)
UniProt:
  • Canonical: P13726 (Residues: 33-251; Coverage: 83%)
Gene name: F3
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6A
Spacegroup: P41212
Unit cell:
a: 45.4Å b: 45.4Å c: 230.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.203 not available
Expression system: PERIPLASMIC SECRETION (U.S PAT 4963,495)

Quick links

Citations

40 review citations

Interleukin-10 and related cytokines and receptors.
Pestka et al. (2004)
39 more

15 mentions without citation

Control of blood proteins by functional disulfide bonds.
Butera et al. (2014)
14 more