Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
homo hexamer (preferred)
Assembly name:
Tyrosine-protein kinase HCK (preferred)
PDBe Complex ID:
PDB-CPX-140252 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase HCK
Molecule details ›
Chains: A, B, C, D, E, F
Length: 57 amino acids
Theoretical weight: 6.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: SH3 domain
Structure domains: SH3 Domains
Length: 57 amino acids
Theoretical weight: 6.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P08631 (Residues: 81-137; Coverage: 11%)
Sequence domains: SH3 domain
Structure domains: SH3 Domains
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE BM02
Spacegroup:
P21212
Expression system: Escherichia coli BL21(DE3)
