› 1bu9

Solution NMR

SOLUTION STRUCTURE OF P18-INK4C, 21 STRUCTURES

Released:
DOI: 10.2210/pdb1bu9/pdb
PDB entry 1bu9 coloured by chain, ensemble of 21 models, front view.
PDB entry 1bu9 coloured by chain, ensemble of 21 models, side view.
PDB entry 1bu9 coloured by chain, ensemble of 21 models, top view.
Source organism: Homo sapiens
Primary publication:
Tumor suppressor INK4: determination of the solution structure of p18INK4C and demonstration of the functional significance of loops in p18INK4C and p16INK4A.
Li J, Byeon IJ, Ericson K, Poi MJ, O'Maille P, Selby T, Tsai MD
Biochemistry 38 2930-40 (1999)
PMID: 10074345

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154868 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cyclin-dependent kinase 4 inhibitor C Chain: A
Molecule details ›
Chain: A
Length: 168 amino acids
Theoretical weight: 18.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P42773 (Residues: 1-168; Coverage: 100%)
Gene names: CDKN2C, CDKN6
Sequence domains: Ankyrin repeats (3 copies)
Structure domains: Ankyrin repeat-containing domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

4 review citations

The ankyrin repeat: a diversity of interactions on a common structural framework.
Sedgwick et al. (1999)
3 more

4 mentions without citation

A primer on ankyrin repeat function in TRP channels and beyond.
Gaudet R. (2008)
3 more