› 1by2

X-ray diffraction
2Å resolution

STRUCTURE OF M2BP SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN

Released:
DOI: 10.2210/pdb1by2/pdb
PDB entry 1by2 coloured by chain, front view.
PDB entry 1by2 coloured by chain, side view.
PDB entry 1by2 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of a scavenger receptor cysteine-rich domain sheds light on an ancient superfamily.
Hohenester E, Sasaki T, Timpl R
Nat Struct Biol 6 228-32 (1999)
PMID: 10074941

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170640 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galectin-3-binding protein Chain: A
Molecule details ›
Chain: A
Length: 119 amino acids
Theoretical weight: 12.71 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q08380 (Residues: 18-133; Coverage: 20%)
Gene names: LGALS3BP, M2BP
Sequence domains: Scavenger receptor cysteine-rich domain
Structure domains: SRCR-like domain

Ligands and Environments

1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELLIOTT GX-21
Spacegroup: P43212
Unit cell:
a: 44.63Å b: 44.63Å c: 134.54Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.186 0.186 0.218
Expression system: Homo sapiens

Quick links

Citations

26 review citations

Origins and functions of B-1 cells with notes on the role of CD5.
Berland et al. (2002)
25 more

16 mentions without citation

Overview of protein structural and functional folds.
Sun et al. (2004)
15 more