Function and Biology Details
Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
homo trimer (preferred)
Assembly name:
TNF receptor-associated factor 2 (preferred)
PDBe Complex ID:
PDB-CPX-171450 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TNF receptor-associated factor 2
Molecule details ›
Chains: A, B, C, D, E, F
Length: 168 amino acids
Theoretical weight: 19.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: TRAF/meprin, MATH domain
Structure domains: Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A
Length: 168 amino acids
Theoretical weight: 19.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
Q12933 (Residues: 334-501; Coverage: 34%)
Sequence domains: TRAF/meprin, MATH domain
Structure domains: Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
CHESS BEAMLINE F2
Spacegroup:
C2
Expression system: Escherichia coli BL21
