› 1cbl

X-ray diffraction
1.8Å resolution

THE 1.9 ANGSTROM STRUCTURE OF DEOXY-BETA4 HEMOGLOBIN: ANALYSIS OF THE PARTITIONING OF QUATERNARY-ASSOCIATED AND LIGAND-INDUCED CHANGES IN TERTIARY STRUCTURE

Released:
DOI: 10.2210/pdb1cbl/pdb
PDB entry 1cbl coloured by chain, front view.
PDB entry 1cbl coloured by chain, side view.
PDB entry 1cbl coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The 1.9 A structure of deoxy beta 4 hemoglobin. Analysis of the partitioning of quaternary-associated and ligand-induced changes in tertiary structure.
Borgstahl GE, Rogers PH, Arnone A
J Mol Biol 236 831-43 (1994)
PMID: 8114097

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159525 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hemoglobin subunit beta Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 146 amino acids
Theoretical weight: 15.89 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P68871 (Residues: 2-147; Coverage: 99%)
Gene name: HBB
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

2 bound ligands:
Ligand SO4 4 x SO4
Ligand HEM 4 x HEM
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 63Å b: 81.8Å c: 54.4Å
α: 90° β: 89.7° γ: 90°
R-values:
R R work R free
0.19 not available not available
Expression system: Not provided

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Citations

1 review citation

A role of heme side-chains of human hemoglobin in its function revealed by circular dichroism and resonance Raman spectroscopy.
Nagai et al. (2018)
10 other articles

2 mentions without citation

Reaction trajectory revealed by a joint analysis of protein data bank.
Ren Z. (2013)
1 more