› 1cdj

X-ray diffraction
2.5Å resolution

STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4

Released:
DOI: 10.2210/pdb1cdj/pdb
PDB entry 1cdj coloured by chain, front view.
PDB entry 1cdj coloured by chain, side view.
PDB entry 1cdj coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding.
Wu H, Myszka DG, Tendian SW, Brouillette CG, Sweet RW, Chaiken IM, Hendrickson WA
Proc Natl Acad Sci U S A 93 15030-5 (1996)
PMID: 8986758

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134521 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
T-cell surface glycoprotein CD4 Chain: A
Molecule details ›
Chain: A
Length: 178 amino acids
Theoretical weight: 19.73 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P01730 (Residues: 26-203; Coverage: 41%)
Gene name: CD4
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 82.7Å b: 30.4Å c: 87.7Å
α: 90° β: 117.3° γ: 90°
R-values:
R R work R free
0.189 0.189 not available
Expression system: Cricetulus griseus

Quick links

Citations

8 review citations

BIAcore for macromolecular interaction.
Fivash et al. (1998)
7 more

9 mentions without citation

Structural interactions of fibroblast growth factor receptor with its ligands.
Stauber et al. (2000)
8 more