› 1ci5

Solution NMR

GLYCAN-FREE MUTANT ADHESION DOMAIN OF HUMAN CD58 (LFA-3)

Released:
DOI: 10.2210/pdb1ci5/pdb
PDB entry 1ci5 coloured by chain, ensemble of 20 models, front view.
PDB entry 1ci5 coloured by chain, ensemble of 20 models, side view.
PDB entry 1ci5 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Functional glycan-free adhesion domain of human cell surface receptor CD58: design, production and NMR studies.
Sun ZY, Dötsch V, Kim M, Li J, Reinherz EL, Wagner G
EMBO J 18 2941-9 (1999)
PMID: 10357807

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148546 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lymphocyte function-associated antigen 3 Chain: A
Molecule details ›
Chain: A
Length: 95 amino acids
Theoretical weight: 11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P19256 (Residues: 29-123; Coverage: 43%)
Gene names: CD58, LFA3
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

5 review citations

Molecular interactions mediating T cell antigen recognition.
van der Merwe et al. (2003)
4 more

1 mention without citation

Two physics-based models for pH-dependent calculations of protein solubility.
Spassov et al. (2022)