Function and Biology Details
Biochemical function:
- not assigned
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131924 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Mothers against decapentaplegic homolog 2
Molecule details ›
Chains: A, C
Length: 196 amino acids
Theoretical weight: 22.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: MH2 domain
Structure domains: Tumour Suppressor Smad4
Length: 196 amino acids
Theoretical weight: 22.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q15796 (Residues: 261-456; Coverage: 42%)
Sequence domains: MH2 domain
Structure domains: Tumour Suppressor Smad4
Zinc finger FYVE domain-containing protein 9
Molecule details ›
Chains: B, D
Length: 41 amino acids
Theoretical weight: 4.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Smad anchor for receptor activation (SARA)
Structure domains: Smad anchor for receptor activation, Smad-binding domain
Length: 41 amino acids
Theoretical weight: 4.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: O95405 (Residues: 771-811; Coverage: 3%)
Sequence domains: Smad anchor for receptor activation (SARA)
Structure domains: Smad anchor for receptor activation, Smad-binding domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSLS BEAMLINE X25
Spacegroup:
P3121
Expression system: Escherichia coli
