› 1df5

X-ray diffraction
2.7Å resolution

INTERACTIONS BETWEEN HIV-1 GP41 CORE AND DETERGENTS AND THEIR IMPLICATIONS FOR MEMBRANE FUSION

Released:
DOI: 10.2210/pdb1df5/pdb
PDB entry 1df5 coloured by chain, front view.
PDB entry 1df5 coloured by chain, side view.
PDB entry 1df5 coloured by chain, top view.
Source organism: Human immunodeficiency virus 1
Primary publication:
Interactions between HIV-1 gp41 core and detergents and their implications for membrane fusion.
Shu W, Ji H, Lu M
J Biol Chem 275 1839-45 (2000)
PMID: 10636883

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137976 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transmembrane protein gp41 Chain: A
Molecule details ›
Chain: A
Length: 68 amino acids
Theoretical weight: 7.88 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Escherichia coli
UniProt:
  • Canonical: P04578 (Residues: 546-655; Coverage: 8%)
Gene name: env
Sequence domains: Retroviral envelope protein
Structure domains: Helix Hairpins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: I213
Unit cell:
a: 72.77Å b: 72.77Å c: 72.77Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.183 0.315
Expression system: Escherichia coli

Quick links

Citations

1 review citation

HIV-1 envelope glycoprotein structure.
Merk et al. (2013)
23 other articles

5 mentions without citation

HPV E6, E6AP and cervical cancer.
Beaudenon et al. (2008)
4 more