› 1dgq

Solution NMR

NMR SOLUTION STRUCTURE OF THE INSERTED DOMAIN OF HUMAN LEUKOCYTE FUNCTION ASSOCIATED ANTIGEN-1

Released:
DOI: 10.2210/pdb1dgq/pdb
PDB entry 1dgq coloured by chain, ensemble of 22 models, front view.
PDB entry 1dgq coloured by chain, ensemble of 22 models, side view.
PDB entry 1dgq coloured by chain, ensemble of 22 models, top view.
Source organism: Homo sapiens
Primary publication:
NMR solution structure of the inserted domain of human leukocyte function associated antigen-1.
Legge GB, Kriwacki RW, Chung J, Hommel U, Ramage P, Case DA, Dyson HJ, Wright PE
J Mol Biol 295 1251-64 (2000)
PMID: 10653701

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149031 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Integrin alpha-L Chain: A
Molecule details ›
Chain: A
Length: 188 amino acids
Theoretical weight: 21.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P20701 (Residues: 149-336; Coverage: 16%)
Gene names: CD11A, ITGAL
Sequence domains: von Willebrand factor type A domain
Structure domains: von Willebrand factor, type A domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: TORSION ANGLE DYNAMICS SIMULATED ANNEALING
Expression system: Escherichia coli

Quick links

Citations

8 review citations

Small-molecule inhibitors of protein-protein interactions: progressing towards the dream.
Arkin et al. (2004)
7 more

5 mentions without citation

Accurate protein structure modeling using sparse NMR data and homologous structure information.
Thompson et al. (2012)
4 more