› 1dks

X-ray diffraction
3.2Å resolution

CKSHS1: HUMAN CYCLIN DEPENDENT KINASE SUBUNIT, TYPE 1 IN COMPLEX WITH PHOSPHATE

Released:
DOI: 10.2210/pdb1dks/pdb
PDB entry 1dks coloured by chain, front view.
PDB entry 1dks coloured by chain, side view.
PDB entry 1dks coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the human cell cycle protein CksHs1: single domain fold with similarity to kinase N-lobe domain.
Arvai AS, Bourne Y, Hickey MJ, Tainer JA
J Mol Biol 249 835-42 (1995)
PMID: 7791211

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158186 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cyclin-dependent kinases regulatory subunit 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 79 amino acids
Theoretical weight: 9.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61024 (Residues: 1-79; Coverage: 100%)
Gene names: CKS1, CKS1B, PNAS-143, PNAS-16
Sequence domains: Cyclin-dependent kinase regulatory subunit
Structure domains: Cyclin-dependent kinase, regulatory subunit

Ligands and Environments

1 bound ligand:
Ligand PO4 2 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P6122
Unit cell:
a: 94Å b: 94Å c: 137.4Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.183 0.183 0.29
Expression system: Escherichia coli

Quick links

Citations

17 review citations

Mechanisms of specificity in protein phosphorylation.
Ubersax et al. (2007)
16 more

7 mentions without citation

Overview of protein structural and functional folds.
Sun et al. (2004)
6 more