› 1dl6

Solution NMR

SOLUTION STRUCTURE OF HUMAN TFIIB N-TERMINAL DOMAIN

Released:
DOI: 10.2210/pdb1dl6/pdb
PDB entry 1dl6 coloured by chain, ensemble of 25 models, front view.
PDB entry 1dl6 coloured by chain, ensemble of 25 models, side view.
PDB entry 1dl6 coloured by chain, ensemble of 25 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure of a (Cys3His) zinc ribbon, a ubiquitous motif in archaeal and eucaryal transcription.
Chen HT, Legault P, Glushka J, Omichinski JG, Scott RA
Protein Sci 9 1743-52 (2000)
PMID: 11045620

Function and Biology Details

Reaction catalysed: 
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine
Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169410 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription initiation factor IIB Chain: A
Molecule details ›
Chain: A
Length: 58 amino acids
Theoretical weight: 6.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q00403 (Residues: 2-59; Coverage: 18%)
Gene names: GTF2B, TF2B, TFIIB
Sequence domains: TFIIB zinc-binding
Structure domains: N-terminal domain of TfIIb

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY SIMULATED ANNEALING TORSION ANGLE DYNAMICS
Expression system: Escherichia coli

Quick links

Citations

8 review citations

Structure and mechanism of the RNA polymerase II transcription machinery.
Hahn S. (2004)
7 more

1 mention without citation

Intrinsic disorder in transcription factors.
Liu et al. (2006)