› 1dqb

Solution NMR

NMR STRUCTURE OF THROMBOMODULIN EGF(4-5)

Released:
DOI: 10.2210/pdb1dqb/pdb
PDB entry 1dqb coloured by chain, ensemble of 12 models, front view.
PDB entry 1dqb coloured by chain, ensemble of 12 models, side view.
PDB entry 1dqb coloured by chain, ensemble of 12 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the smallest cofactor-active fragment of thrombomodulin.
Wood MJ, Sampoli Benitez BA, Komives EA
Nat Struct Biol 7 200-4 (2000)
PMID: 10700277

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139431 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thrombomodulin Chain: A
Molecule details ›
Chain: A
Length: 83 amino acids
Theoretical weight: 9.3 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P07204 (Residues: 362-444; Coverage: 15%)
Gene names: THBD, THRM
Sequence domains: Complement Clr-like EGF-like
Structure domains: Laminin

Ligands and Environments

1 bound ligand:
Ligand NAG 2 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry simulated annealing refinment
Expression system: Komagataella pastoris

Quick links

Citations

12 review citations

Thrombomodulin.
Weiler et al. (2003)
11 more

2 mentions without citation

Predicted structural mimicry of spike receptor-binding motifs from highly pathogenic human coronaviruses.
Beaudoin et al. (2021)
1 more