Function and Biology Details
Reaction catalysed:
Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa.
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- EGF-like domain
- Peptidase S1A, chymotrypsin family
- Serine proteases, trypsin domain
- Peptidase S1, PA clan, chymotrypsin-like fold
- EGF-type aspartate/asparagine hydroxylation site
- EGF-like calcium-binding, conserved site
- EGF-like calcium-binding domain
- Serine proteases, trypsin family, serine active site
2 more domains
Structure domains:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140355 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Factor VII heavy chain
Molecule details ›
Chains: H, I
Length: 254 amino acids
Theoretical weight: 28.1 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Length: 254 amino acids
Theoretical weight: 28.1 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
P08709 (Residues: 213-466; Coverage: 57%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Factor VII light chain
Molecule details ›
Chains: L, M
Length: 101 amino acids
Theoretical weight: 10.99 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Structure domains: Laminin
Length: 101 amino acids
Theoretical weight: 10.99 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P08709 (Residues: 102-202; Coverage: 23%)
Sequence domains:
Structure domains: Laminin
