1dxs

X-ray diffraction
2.54Å resolution

Crystal structure of the C-terminal sterile alpha motif (SAM) domain of human p73 alpha splice variant

Released:
Source organism: Homo sapiens
Primary publication:
Structure of the C-terminal sterile alpha-motif (SAM) domain of human p73 alpha.
Acta Crystallogr D Biol Crystallogr 57 545-51 (2001)
PMID: 11264583

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127438 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tumor protein p73 Chain: A
Molecule details ›
Chain: A
Length: 80 amino acids
Theoretical weight: 9.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O15350 (Residues: 487-564; Coverage: 12%)
Gene names: P73, TP73
Sequence domains: SAM domain (Sterile alpha motif)
Structure domains: Transcription Factor, Ets-1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P41212
Unit cell:
a: 32.02Å b: 32.02Å c: 133.84Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.275 0.275 0.346
Expression system: Escherichia coli BL21(DE3)