1ee5

X-ray diffraction
2.4Å resolution

YEAST KARYOPHERIN (IMPORTIN) ALPHA IN A COMPLEX WITH A NUCLEOPLASMIN NLS PEPTIDE

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-138600 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Importin subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 424 amino acids
Theoretical weight: 46.93 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Not provided
UniProt:
  • Canonical: Q02821 (Residues: 87-510; Coverage: 78%)
Gene names: KAP60, N1606, SRP1, YNL189W
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Nucleoplasmin Chain: B
Molecule details ›
Chain: B
Length: 19 amino acids
Theoretical weight: 2.03 KDa
Source organism: Xenopus laevis
Expression system: Not provided
UniProt:
  • Canonical: P05221 (Residues: 153-171; Coverage: 10%)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: C2
Unit cell:
a: 157.56Å b: 63.7Å c: 62.15Å
α: 90° β: 97.34° γ: 90°
R-values:
R R work R free
0.241 0.241 0.265
Expression system: Not provided