Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
General transcription factor TFIIF complex (preferred)
PDBe Complex ID:
PDB-CPX-146829 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
General transcription factor IIF subunit 2
Molecule details ›
Chains: A, C, E, G
Length: 118 amino acids
Theoretical weight: 12.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: TFIIF, beta subunit N-terminus
Length: 118 amino acids
Theoretical weight: 12.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P13984 (Residues: 2-119; Coverage: 47%)
Sequence domains: TFIIF, beta subunit N-terminus
General transcription factor IIF subunit 1
Molecule details ›
Chains: B, D, F, H
Length: 171 amino acids
Theoretical weight: 19.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
Length: 171 amino acids
Theoretical weight: 19.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P35269 (Residues: 2-172; Coverage: 33%)
Sequence domains: Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID14-4
Spacegroup:
P1
Expression system: Escherichia coli
