› 1f4i

Solution NMR

SOLUTION STRUCTURE OF THE HHR23A UBA(2) MUTANT P333E, DEFICIENT IN BINDING THE HIV-1 ACCESSORY PROTEIN VPR

Released:
DOI: 10.2210/pdb1f4i/pdb
PDB entry 1f4i coloured by chain, ensemble of 21 models, front view.
PDB entry 1f4i coloured by chain, ensemble of 21 models, side view.
PDB entry 1f4i coloured by chain, ensemble of 21 models, top view.
Source organism: Homo sapiens
Primary publication:
Biochemical and structural analysis of the interaction between the UBA(2) domain of the DNA repair protein HHR23A and HIV-1 Vpr.
Withers-Ward ES, Mueller TD, Chen IS, Feigon J
Biochemistry 39 14103-12 (2000)
PMID: 11087358

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157078 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
UV excision repair protein RAD23 homolog A Chain: A
Molecule details ›
Chain: A
Length: 45 amino acids
Theoretical weight: 5.18 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P54725 (Residues: 319-363; Coverage: 12%)
Gene name: RAD23A
Sequence domains: UBA/TS-N domain
Structure domains: DNA helicase RuvA subunit, C-terminal domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, distance geometry
Expression system: Not provided

Quick links

Citations

8 review citations

Ubiquitin-binding domains.
Hicke et al. (2005)
7 more

7 mentions without citation

An all-atom force field for tertiary structure prediction of helical proteins.
Herges et al. (2004)
6 more