› 1f9s

X-ray diffraction
2.38Å resolution

CRYSTAL STRUCTURE OF PLATELET FACTOR 4 MUTANT 2

Released:
DOI: 10.2210/pdb1f9s/pdb
PDB entry 1f9s coloured by chain, front view.
PDB entry 1f9s coloured by chain, side view.
PDB entry 1f9s coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Yang J, Doyle M, Faulk T, Visentin G, Aster R, Edwards B

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136202 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Platelet factor 4 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 70 amino acids
Theoretical weight: 7.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02776 (Residues: 32-101; Coverage: 100%)
Gene names: CXCL4, PF4, SCYB4
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 80.4Å b: 77.48Å c: 42.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.228 0.288
Expression system: Escherichia coli

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