› 1fb5

X-ray diffraction
3.5Å resolution

LOW RESOLUTION STRUCTURE OF OVINE ORNITHINE TRANSCARBMOYLASE IN THE UNLIGANDED STATE

Released:
DOI: 10.2210/pdb1fb5/pdb
PDB entry 1fb5 coloured by chain, front view.
PDB entry 1fb5 coloured by chain, side view.
PDB entry 1fb5 coloured by chain, top view.
Source organism: Ovis aries
Primary publication:
Functional and structural characterization of ovine ornithine transcarbamoylase.
De Gregorio A, Battistutta R, Arena N, Panzalorto M, Francescato P, Valentini G, Bruno G, Zanotti G
Org Biomol Chem 1 3178-85 (2003)
PMID: 14527149

Function and Biology Details

Reaction catalysed: 
Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160783 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ornithine transcarbamylase, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 320 amino acids
Theoretical weight: 35.89 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: P84010 (Residues: 36-355; Coverage: 90%)
Gene name: OTC
Sequence domains:
Structure domains: Aspartate/ornithine carbamoyltransferase

Ligands and Environments

1 bound ligand:
Ligand NVA 1 x NVA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELETTRA BEAMLINE 5.2R
Spacegroup: P4332
Unit cell:
a: 184.7Å b: 184.7Å c: 184.7Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.212 0.252

Quick links

Citations

1 review citation

From Genome to Structure and Back Again: A Family Portrait of the Transcarbamylases.
Shi et al. (2015)
4 other articles

2 mentions without citation

New insight into the transcarbamylase family: the structure of putrescine transcarbamylase, a key catalyst for fermentative utilization of agmatine.
Polo et al. (2012)
1 more