› 1fbi

X-ray diffraction
3Å resolution

CRYSTAL STRUCTURE OF A CROSS-REACTION COMPLEX BETWEEN FAB F9.13.7 AND GUINEA-FOWL LYSOZYME

Released:
DOI: 10.2210/pdb1fbi/pdb
PDB entry 1fbi coloured by chain, front view.
PDB entry 1fbi coloured by chain, side view.
PDB entry 1fbi coloured by chain, top view.
Source organisms:
Primary publication:
Crystal structure of a cross-reaction complex between Fab F9.13.7 and guinea fowl lysozyme.
Lescar J, Pellegrini M, Souchon H, Tello D, Poljak RJ, Peterson N, Greene M, Alzari PM
J Biol Chem 270 18067-76 (1995)
PMID: 7629116

Function and Biology Details

Reaction catalysed: 
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-132929 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Immunoglobulin kappa constant Chains: L, P
Molecule details ›
Chains: L, P
Length: 214 amino acids
Theoretical weight: 23.83 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: P01837 (Residues: 1-107; Coverage: 100%)
Gene name: Igkc
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Ig gamma-1 chain C region secreted form Chains: H, Q
Molecule details ›
Chains: H, Q
Length: 221 amino acids
Theoretical weight: 23.63 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: P01868 (Residues: 1-99; Coverage: 31%)
Gene names: Igh-4, Ighg1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Lysozyme C Chains: X, Y
Molecule details ›
Chains: X, Y
Length: 129 amino acids
Theoretical weight: 14.33 KDa
Source organism: Numida meleagris
Expression system: Not provided
UniProt:
  • Canonical: P00704 (Residues: 1-129; Coverage: 100%)
Gene name: LYZ
Sequence domains: C-type lysozyme/alpha-lactalbumin family
Structure domains: Lysozyme

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 83.7Å b: 195.5Å c: 50.2Å
α: 90° β: 108.5° γ: 90°
R-values:
R R work R free
0.19 0.19 not available
Expression system: Not provided

Quick links

Citations

10 review citations

From natural polyreactive autoantibodies to à la carte monoreactive antibodies to infectious agents: is it a small world after all?
Bouvet et al. (1998)
9 more

28 mentions without citation

The Neonatal Fc Receptor (FcRn): A Misnomer?
Pyzik et al. (2019)
27 more