› 1fex

Solution NMR

SOLUTION STRUCTURE OF MYB-DOMAIN OF HUMAN RAP1

Released:
DOI: 10.2210/pdb1fex/pdb
PDB entry 1fex coloured by chain, ensemble of 25 models, front view.
PDB entry 1fex coloured by chain, ensemble of 25 models, side view.
PDB entry 1fex coloured by chain, ensemble of 25 models, top view.
Source organism: Homo sapiens
Primary publication:
NMR structure of the hRap1 Myb motif reveals a canonical three-helix bundle lacking the positive surface charge typical of Myb DNA-binding domains.
Hanaoka S, Nagadoi A, Yoshimura S, Aimoto S, Li B, de Lange T, Nishimura Y
J Mol Biol 312 167-75 (2001)
PMID: 11545594

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192701 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Telomeric repeat-binding factor 2-interacting protein 1 Chain: A
Molecule details ›
Chain: A
Length: 59 amino acids
Theoretical weight: 6.66 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9NYB0 (Residues: 132-190; Coverage: 15%)
Gene names: DRIP5, PP8000, RAP1, TERF2IP
Sequence domains: Rap1 Myb domain
Structure domains: Homeodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry simulated annealing
Expression system: Not provided

Quick links

Citations

13 review citations

How shelterin protects mammalian telomeres.
Palm et al. (2008)
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9 mentions without citation

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Nickson et al. (2010)
8 more