› 1fil

X-ray diffraction
2Å resolution

HUMAN PLATELET PROFILIN I CRYSTALLIZED IN HIGH SALT ACTIN-BINDING PROTEIN

Released:
DOI: 10.2210/pdb1fil/pdb
PDB entry 1fil coloured by chain, front view.
PDB entry 1fil coloured by chain, side view.
PDB entry 1fil coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Fedorov AA, Pollard TD, Almo SC

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139726 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Profilin-1 Chain: A
Molecule details ›
Chain: A
Length: 139 amino acids
Theoretical weight: 14.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P07737 (Residues: 2-140; Coverage: 99%)
Gene name: PFN1
Sequence domains: Profilin
Structure domains: Dynein light chain 2a, cytoplasmic

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: C2
Unit cell:
a: 75.05Å b: 31.77Å c: 62.82Å
α: 90° β: 123.41° γ: 90°
R-values:
R R work R free
0.191 0.191 not available
Expression system: Escherichia coli

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