Function and Biology Details
Reaction catalysed:
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assemblies composition:
Assembly name:
PDBe Complex ID:
PDB-CPX-158903 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Rho guanine nucleotide exchange factor TIAM1
Molecule details ›
Chains: A, C, E, G
Length: 377 amino acids
Theoretical weight: 43.83 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: RhoGEF domain
Structure domains:
Length: 377 amino acids
Theoretical weight: 43.83 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q60610 (Residues: 1030-1406; Coverage: 24%)
Sequence domains: RhoGEF domain
Structure domains:
Ras-related C3 botulinum toxin substrate 1
Molecule details ›
Chains: B, D, F, H
Length: 177 amino acids
Theoretical weight: 19.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Length: 177 amino acids
Theoretical weight: 19.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P63000 (Residues: 1-177; Coverage: 92%)
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
