1frg

X-ray diffraction
2.8Å resolution

CRYSTAL STRUCTURE, SEQUENCE, AND EPITOPE MAPPING OF A PEPTIDE COMPLEX OF AN ANTI-INFLUENZA HA PEPTIDE ANTIBODY FAB 26(SLASH)9: FINE-TUNING ANTIBODY SPECIFICITY

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-122926 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Immunoglobulin kappa constant Chain: L
Molecule details ›
Chain: L
Length: 217 amino acids
Theoretical weight: 24.03 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: P01837 (Residues: 1-104; Coverage: 97%)
Gene name: Igkc
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Ig gamma-2A chain C region secreted form Chain: H
Molecule details ›
Chain: H
Length: 220 amino acids
Theoretical weight: 23.76 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: P01864 (Residues: 1-98, 100-100; Coverage: 30%)
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Hemagglutinin Chain: P
Molecule details ›
Chain: P
Length: 10 amino acids
Theoretical weight: 903 Da
Source organism: Influenza A virus (A/Assam/2112/2009(H3N2))
Expression system: Not provided
UniProt:
  • Canonical: E3W6A8 (Residues: 7-14; Coverage: 13%)
Gene name: HA

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 66.6Å b: 115.1Å c: 73.3Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.19 not available
Expression system: Not provided