› 1g25

Solution NMR

SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF THE HUMAN TFIIH MAT1 SUBUNIT

Released:
DOI: 10.2210/pdb1g25/pdb
PDB entry 1g25 coloured by chain, ensemble of 20 models, front view.
PDB entry 1g25 coloured by chain, ensemble of 20 models, side view.
PDB entry 1g25 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the N-terminal domain of the human TFIIH MAT1 subunit: new insights into the RING finger family.
Gervais V, Busso D, Wasielewski E, Poterszman A, Egly JM, Thierry JC, Kieffer B
J Biol Chem 276 7457-64 (2001)
PMID: 11056162

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156437 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CDK-activating kinase assembly factor MAT1 Chain: A
Molecule details ›
Chain: A
Length: 65 amino acids
Theoretical weight: 7.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P51948 (Residues: 1-65; Coverage: 21%)
Gene names: CAP35, MAT1, MNAT1, RNF66
Sequence domains: Zinc finger, C3HC4 type (RING finger)
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Structural basis of transcription initiation by RNA polymerase II.
Sainsbury et al. (2015)
3 more

8 mentions without citation

XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase.
Fuss et al. (2011)
7 more