› 1gd5

Solution NMR

SOLUTION STRUCTURE OF THE PX DOMAIN FROM HUMAN P47PHOX NADPH OXIDASE

Released:
DOI: 10.2210/pdb1gd5/pdb
PDB entry 1gd5 coloured by chain, ensemble of 20 models, front view.
PDB entry 1gd5 coloured by chain, ensemble of 20 models, side view.
PDB entry 1gd5 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the PX domain, a target of the SH3 domain.
Hiroaki H, Ago T, Ito T, Sumimoto H, Kohda D
Nat Struct Biol 8 526-30 (2001)
PMID: 11373621

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146972 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neutrophil cytosol factor 1 Chain: A
Molecule details ›
Chain: A
Length: 130 amino acids
Theoretical weight: 15.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P14598 (Residues: 1-128; Coverage: 33%)
Gene names: NCF1, NOXO2, SH3PXD1A
Sequence domains: PX domain
Structure domains: Phox-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

35 review citations

NOX enzymes and the biology of reactive oxygen.
Lambeth JD. (2004)
34 more

8 mentions without citation

Activation and assembly of the NADPH oxidase: a structural perspective.
Groemping et al. (2005)
7 more