› 1gg3

X-ray diffraction
2.8Å resolution

CRYSTAL STRUCTURE OF THE PROTEIN 4.1R MEMBRANE BINDING DOMAIN

Released:
DOI: 10.2210/pdb1gg3/pdb
PDB entry 1gg3 coloured by chain, front view.
PDB entry 1gg3 coloured by chain, side view.
PDB entry 1gg3 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization.
Han BG, Nunomura W, Takakuwa Y, Mohandas N, Jap BK
Nat Struct Biol 7 871-5 (2000)
PMID: 11017195

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145690 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein 4.1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 279 amino acids
Theoretical weight: 32.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P11171 (Residues: 210-488; Coverage: 32%)
Gene names: E41P, EPB41
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: C2
Unit cell:
a: 163.9Å b: 106.5Å c: 93.5Å
α: 90° β: 95.5° γ: 90°
R-values:
R R work R free
0.226 0.226 0.276
Expression system: Escherichia coli

Quick links

Citations

16 review citations

Principles of interleukin (IL)-6-type cytokine signalling and its regulation.
Heinrich et al. (2003)
15 more

15 mentions without citation

Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus.
Tarpey et al. (2006)
14 more