Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Nuclear cap-binding complex (preferred)
PDBe Complex ID:
PDB-CPX-156542 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nuclear cap-binding protein subunit 1
Molecule details ›
Chains: A, B, C
Length: 757 amino acids
Theoretical weight: 87.94 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains:
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Length: 757 amino acids
Theoretical weight: 87.94 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
Q09161 (Residues: 20-790; Coverage: 96%)
Sequence domains:
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Nuclear cap-binding protein subunit 2
Molecule details ›
Chains: X, Y, Z
Length: 98 amino acids
Theoretical weight: 11.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits
Length: 98 amino acids
Theoretical weight: 11.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical: P52298 (Residues: 22-120; Coverage: 63%)
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID14-2
Spacegroup:
P212121
Expression systems:
- Trichoplusia ni
- Escherichia coli BL21
