› 1h95

Solution NMR

Solution structure of the single-stranded DNA-binding Cold Shock Domain (CSD) of human Y-box protein 1 (YB1) determined by NMR (10 lowest energy structures)

Released:
DOI: 10.2210/pdb1h95/pdb
PDB entry 1h95 coloured by chain, ensemble of 10 models, front view.
PDB entry 1h95 coloured by chain, ensemble of 10 models, side view.
PDB entry 1h95 coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
The solution structure and DNA-binding properties of the cold-shock domain of the human Y-box protein YB-1.
Kloks CP, Spronk CA, Lasonder E, Hoffmann A, Vuister GW, Grzesiek S, Hilbers CW
J Mol Biol 316 317-26 (2002)
PMID: 11851341

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159232 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Y-box-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 79 amino acids
Theoretical weight: 8.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P67809 (Residues: 52-129; Coverage: 24%)
Gene names: NSEP1, YB1, YBX1
Sequence domains: 'Cold-shock' DNA-binding domain
Structure domains: Nucleic acid-binding proteins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: TORSION ANGLE DYNAMICS FOLLOWED BY RESTRAINED MD
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

18 review citations

The pleiotropic functions of the Y-box-binding protein, YB-1.
Kohno et al. (2003)
17 more

11 mentions without citation

New targets for HIV drug discovery.
Puhl et al. (2019)
10 more