› 1haq

X-ray solution scattering

FOUR MODELS OF HUMAN FACTOR H DETERMINED BY SOLUTION SCATTERING CURVE-FITTING AND HOMOLOGY MODELLING

Released:
DOI: 10.2210/pdb1haq/pdb
PDB entry 1haq coloured by chain, ensemble of 4 models, front view.
PDB entry 1haq coloured by chain, ensemble of 4 models, side view.
PDB entry 1haq coloured by chain, ensemble of 4 models, top view.
Source organism: Homo sapiens
Primary publication:
Folded-back solution structure of monomeric factor H of human complement by synchrotron X-ray and neutron scattering, analytical ultracentrifugation and constrained molecular modelling.
Aslam M, Perkins SJ
J Mol Biol 309 1117-38 (2001)
PMID: 11399083

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140213 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Complement factor H Chain: A
Molecule details ›
Chain: A
Length: 1213 amino acids
Theoretical weight: 137.24 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P08603 (Residues: 19-1231; Coverage: 100%)
Gene names: CFH, HF, HF1, HF2
Sequence domains: Sushi repeat (SCR repeat)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Quick links

Citations

24 review citations

X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution.
Putnam et al. (2007)
23 more

1 mention without citation

The Epigenetic Dimension of Protein Structure Is an Intrinsic Weakness of the AlphaFold Program.
Azzaz et al. (2022)