› 1hkg

X-ray diffraction
3.5Å resolution

STRUCTURAL DYNAMICS OF YEAST HEXOKINASE DURING CATALYSIS

Released:
DOI: 10.2210/pdb1hkg/pdb
PDB entry 1hkg coloured by chain, front view.
PDB entry 1hkg coloured by chain, side view.
PDB entry 1hkg coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structural dynamics of yeast hexokinase during catalysis.
Steitz TA, Shoham M, Bennett WS
Philos Trans R Soc Lond B Biol Sci 293 43-52 (1981)
PMID: 6115422

Function and Biology Details

Reaction catalysed: 
ATP + D-hexose = ADP + D-hexose 6-phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138188 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hexokinase-1 Chain: A
Molecule details ›
Chain: A
Length: 457 amino acids
Theoretical weight: 46.02 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Not provided
UniProt:
  • Canonical: P04806 (Residues: 26-448, 449-470; Coverage: 89%)
Gene names: HKA, HXK1, YFR053C
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 144.8Å b: 78.8Å c: 61.9Å
α: 90° β: 90° γ: 90°
Expression system: Not provided

Quick links

Citations

8 review citations

Is allostery an intrinsic property of all dynamic proteins?
Gunasekaran et al. (2004)
7 more

4 mentions without citation

Isotope-Labeled RNA Building Blocks for NMR Structure and Dynamics Studies.
Olenginski et al. (2021)
3 more