› 1htn

X-ray diffraction
2.8Å resolution

HUMAN TETRANECTIN, A TRIMERIC PLASMINOGEN BINDING PROTEIN WITH AN ALPHA-HELICAL COILED COIL

Released:
DOI: 10.2210/pdb1htn/pdb
PDB entry 1htn coloured by chain, front view.
PDB entry 1htn coloured by chain, side view.
PDB entry 1htn coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of tetranectin, a trimeric plasminogen-binding protein with an alpha-helical coiled coil.
Nielsen BB, Kastrup JS, Rasmussen H, Holtet TL, Graversen JH, Etzerodt M, Thøgersen HC, Larsen IK
FEBS Lett 412 388-96 (1997)
PMID: 9256258

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138674 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tetranectin Chain: A
Molecule details ›
Chain: A
Length: 182 amino acids
Theoretical weight: 20.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05452 (Residues: 22-202; Coverage: 100%)
Gene names: CLEC3B, TNA
Sequence domains: Lectin C-type domain
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

1 bound ligand:
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: R3
Unit cell:
a: 89.14Å b: 89.14Å c: 75.77Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.223 0.223 0.292
Expression system: Escherichia coli

Quick links

Citations

9 review citations

C-type lectin-like domains.
Drickamer K. (1999)
8 more

7 mentions without citation

Peptide aptamers: development and applications.
Reverdatto et al. (2015)
6 more