1hu3

X-ray diffraction
2.37Å resolution

MIDDLE DOMAIN OF HUMAN EIF4GII

Released:

Function and Biology Details

Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-128927 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Eukaryotic translation initiation factor 4 gamma 3 Chain: A
Molecule details ›
Chain: A
Length: 260 amino acids
Theoretical weight: 30.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O43432 (Residues: 745-1003; Coverage: 16%)
Gene name: EIF4G3
Sequence domains: MIF4G domain
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: R3
Unit cell:
a: 118.8Å b: 118.8Å c: 58.2Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.249 0.249 0.295
Expression system: Escherichia coli BL21(DE3)