1hul

X-ray diffraction
2.4Å resolution

A NOVEL DIMER CONFIGURATION REVEALED BY THE CRYSTAL STRUCTURE AT 2.4 ANGSTROMS RESOLUTION OF HUMAN INTERLEUKIN-5

Released:

Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138517 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interleukin-5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 108 amino acids
Theoretical weight: 12.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05113 (Residues: 24-131; Coverage: 94%)
Gene name: IL5
Sequence domains: Interleukin 5
Structure domains: Growth Hormone; Chain: A;

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 122.1Å b: 36.11Å c: 56.42Å
α: 90° β: 98.59° γ: 90°
R-values:
R R work R free
0.213 0.213 0.369
Expression system: Escherichia coli