› 1hyj

Solution NMR

SOLUTION STRUCTURE OF THE EEA1 FYVE DOMAIN

Released:
DOI: 10.2210/pdb1hyj/pdb
PDB entry 1hyj coloured by chain, ensemble of 20 models, front view.
PDB entry 1hyj coloured by chain, ensemble of 20 models, side view.
PDB entry 1hyj coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural mechanism of endosome docking by the FYVE domain.
Kutateladze T, Overduin M
Science 291 1793-6 (2001)
PMID: 11230696

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172185 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Early endosome antigen 1 Chain: A
Molecule details ›
Chain: A
Length: 65 amino acids
Theoretical weight: 7.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15075 (Residues: 1347-1411; Coverage: 5%)
Gene names: EEA1, ZFYVE2
Sequence domains: FYVE zinc finger
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

29 review citations

Membrane recognition by phospholipid-binding domains.
Lemmon MA. (2008)
28 more

3 mentions without citation

Translation of the phosphoinositide code by PI effectors.
Kutateladze TG. (2010)
2 more