› 1hyn

X-ray diffraction
2.6Å resolution

CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF HUMAN ERYTHROCYTE BAND-3 PROTEIN

Released:
DOI: 10.2210/pdb1hyn/pdb
PDB entry 1hyn coloured by chain, front view.
PDB entry 1hyn coloured by chain, side view.
PDB entry 1hyn coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystallographic structure and functional interpretation of the cytoplasmic domain of erythrocyte membrane band 3.
Zhang D, Kiyatkin A, Bolin JT, Low PS
Blood 96 2925-33 (2000)
PMID: 11049968

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo octamer
Assembly name:
PDBe Complex ID:
PDB-CPX-136111 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Band 3 anion transport protein Chains: P, Q, R, S
Molecule details ›
Chains: P, Q, R, S
Length: 379 amino acids
Theoretical weight: 42.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02730 (Residues: 1-379; Coverage: 42%)
Gene names: AE1, DI, EPB3, SLC4A1
Sequence domains: Band 3 cytoplasmic domain
Structure domains: Mannitol-specific EII; Chain A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-D
Spacegroup: C2
Unit cell:
a: 181.59Å b: 92.58Å c: 123.33Å
α: 90° β: 131.86° γ: 90°
R-values:
R R work R free
0.216 0.216 0.29
Expression system: Escherichia coli

Quick links

Citations

45 review citations

The SLC4 family of HCO 3 - transporters.
Romero et al. (2004)
44 more

33 mentions without citation

To Tie or Not to Tie? That Is the Question.
Dabrowski-Tumanski et al. (2017)
32 more