Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Cadherin-1 and Catenin beta-1 (preferred)
PDBe Complex ID:
PDB-CPX-140759 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Catenin beta-1
Molecule details ›
Chains: A, C
Length: 538 amino acids
Theoretical weight: 58.84 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: Armadillo/beta-catenin-like repeat
Structure domains: Leucine-rich Repeat Variant
Length: 538 amino acids
Theoretical weight: 58.84 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q02248 (Residues: 134-671; Coverage: 69%)
Sequence domains: Armadillo/beta-catenin-like repeat
Structure domains: Leucine-rich Repeat Variant
E-Cad/CTF2
Molecule details ›
Chains: B, D
Length: 151 amino acids
Theoretical weight: 17 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: Cadherin, Y-type LIR-motif
Structure domains: TCF3-CBD (Catenin binding domain)
Length: 151 amino acids
Theoretical weight: 17 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical: P09803 (Residues: 734-884; Coverage: 18%)
Sequence domains: Cadherin, Y-type LIR-motif
Structure domains: TCF3-CBD (Catenin binding domain)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SSRL BEAMLINE BL9-2
Spacegroup:
C2
Expression system: Escherichia coli
