Function and Biology Details
Reaction catalysed:
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Inositol-1,4,5-trisphosphate 5-phosphatase 1 (preferred)
PDBe Complex ID:
PDB-CPX-128822 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inositol-1,4,5-trisphosphate 5-phosphatase 1
Molecule details ›
Chain: A
Length: 347 amino acids
Theoretical weight: 40.09 KDa
Source organism: Schizosaccharomyces pombe
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Endonuclease/Exonuclease/phosphatase family
Structure domains: Endonuclease/exonuclease/phosphatase
Length: 347 amino acids
Theoretical weight: 40.09 KDa
Source organism: Schizosaccharomyces pombe
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
O43001 (Residues: 534-880; Coverage: 32%)
Sequence domains: Endonuclease/Exonuclease/phosphatase family
Structure domains: Endonuclease/exonuclease/phosphatase
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU RU300
Spacegroup:
C2
Expression system: Escherichia coli BL21(DE3)
